1194453-23-0
1194453-23-0 structure
- Name: BAY-8040
- Chemical Name: BAY8040
- CAS Number: 1194453-23-0
- Molecular Formula:
- Molecular Weight:
- Create Date: 2018-06-18 16:51:10
- Modify Date: 2024-10-07 20:05:53
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Bay-8040 is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 28 nM; displays no significant inhibition toward 68 other pharmacologically relevant targets (>10 uM), and a panel of related serine proteases; shows in vivo efficacy with regard to decreasing cardiac remodeling and amelioration of cardiac function in monocrotaline-induced rat model for pulmonary arterial hypertension.
| Name | BAY8040 |
|---|
| No Any Chemical & Physical Properties |