172971-76-5
172971-76-5 structure
- Name: MHI-148
- Chemical Name: MHI-148
- CAS Number: 172971-76-5
- Molecular Formula: C42H52ClN2O4.Br
- Molecular Weight: 764.24
- Catalog: Research Areas Cancer
- Create Date: 2018-06-30 07:42:19
- Modify Date: 2024-01-12 09:46:10
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MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and treatment. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1].
| Name | MHI-148 |
|---|---|
| Synonyms | MHI-148 |
| Description | MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and treatment. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1]. |
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| Related Catalog | |
| In Vitro | MHI-148 (10 µM, 1 h) is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties[1]. MHI-148 (0-1.5 µM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells[1]. |
| Molecular Formula | C42H52ClN2O4.Br |
|---|---|
| Molecular Weight | 764.24 |
| Hazard Codes | Xn |
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