99027-06-2

99027-06-2 structure

Name: C3d Peptide P16
Chemical Name: C3D PEPTIDE P16
CAS Number: 99027-06-2
Molecular Formula: C₈₆H₁₃₁N₂₅O₂₇
Molecular Weight: 265.305
Catalog: Research Areas Cancer
Create Date: 2018-06-12 11:55:41
Modify Date: 2024-01-19 21:03:24
C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2].

Name	C3D PEPTIDE P16
Synonyms	L-Phenylalanine, N-(2-hydroxyacetyl)-2,6-dimethyl-, methyl ester Methyl N-glycoloyl-2,6-dimethyl-L-phenylalaninate

Description	C3 Peptide P16, is a 16 amino acid synthetic peptide derived from human C3d, a fragment generated in trypsin-cleaved C3. C3 Peptide P16 enhances in vitro phosphorylation of pp105 and pp100, a cellular component presenting in the human B lymphoma cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	C3 Peptide P16 (7.4 μM; 18 h) triggers in vitro and in vivo phosphorylations and in vitro proliferation of human B lymphocytes, depending on the stage of cell differentiation[1]. C3 Peptide P16 (7 nM; 60 min; 4 ℃) induces in vivo tyrosine phosphorylation of pp105 and (15 μM; 6-8 d) enhances proliferation only of CR2-pos. but not of CR2-neg. cell lines in vitro[1]. C3 Peptide P16 (7.4 μM; 18 h) also induces in vivo tyrosine phosphorylation of pp100 and in vivo proliferation of only small dense resting B lymphocytes and not other B lymphocyte subpopulations nor T lymphocytes[1]. C3 Peptide P16 (0.3-10 μM; 3 min; 33 ℃) dose-dependently regulates pp105 phosphorylation, as well as C3d fragment present in trypsin-cleaved C3[2].