Shanghai Nianxing Industrial Co., Ltd
China
Product Name: QX-77
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: QX-77
Price: $550.0/100mg $950.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: QX-77
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

1798331-92-6

1798331-92-6 structure

1798331-92-6 structure

Name: QX-77
Chemical Name: QX77
CAS Number: 1798331-92-6
Molecular Formula: C₁₆H₁₃ClN₂O₂
Molecular Weight: 300.74
Catalog: Research Areas Cancer
Create Date: 2018-09-04 18:11:42
Modify Date: 2025-08-26 16:42:12
QX77 is a chaperone-mediated autophagy (CMA) activator.

Name	QX77

Description	QX77 is a chaperone-mediated autophagy (CMA) activator.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	CMA[1]
In Vitro	Treatment with CMA activator QX77 rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells. QX77 treatment also increases LAMP2A localization at the lysosomal membrane[1].
Cell Assay	Mouse embryo fibroblasts are preincubated with QX77 or vehicle (DMSO) 48 h before the addition of tert-butyl hydroperoxide. After an overnight incubation, cell viability is determined by a modified version of the MTT assay[1].
References	[1]. Zhang J, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017 Jun 23;292(25):10328-10346.

Molecular Formula	C₁₆H₁₃ClN₂O₂
Molecular Weight	300.74
Storage condition	2-8℃

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.