2138498-18-5

2138498-18-5 structure
2138498-18-5 structure
  • Name: diABZI STING agonist-1 (Tautomerism)
  • Chemical Name: diABZI STING agonist-1 Tautomerism
  • CAS Number: 2138498-18-5
  • Molecular Formula: C42H51N13O7
  • Molecular Weight: 849.94
  • Catalog: Signaling Pathways Immunology/Inflammation STING
  • Create Date: 2019-02-08 19:16:25
  • Modify Date: 2025-08-24 18:25:56
  • diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

Name diABZI STING agonist-1 Tautomerism
Description diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
Related Catalog
Target

EC50: 130 nM (human STNG in PBMCs) [1].

In Vitro diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
In Vivo diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].
References

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

Molecular Formula C42H51N13O7
Molecular Weight 849.94
Storage condition -20°C
Hazard Codes Xn
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