diABZI STING agonist-1 (Tautomerism)

Modify Date: 2025-08-24 18:25:56

diABZI STING agonist-1 (Tautomerism) Structure
diABZI STING agonist-1 (Tautomerism) structure
Common Name diABZI STING agonist-1 (Tautomerism)
CAS Number 2138498-18-5 Molecular Weight 849.94
Density N/A Boiling Point N/A
Molecular Formula C42H51N13O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of diABZI STING agonist-1 (Tautomerism)


diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

 Names

Name diABZI STING agonist-1 Tautomerism

 diABZI STING agonist-1 (Tautomerism) Biological Activity

Description diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
Related Catalog
Target

EC50: 130 nM (human STNG in PBMCs) [1].

In Vitro diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.
In Vivo diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].
References

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.

 Chemical & Physical Properties

Molecular Formula C42H51N13O7
Molecular Weight 849.94
Storage condition -20°C

 Safety Information

Hazard Codes Xn
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