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2229042-77-5

2229042-77-5 structure
2229042-77-5 structure
  • Name: ZL0454
  • Chemical Name: ZL0454
  • CAS Number: 2229042-77-5
  • Molecular Formula: C18H22N4O3S
  • Molecular Weight: 374.46
  • Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
  • Create Date: 2019-03-31 07:38:33
  • Modify Date: 2024-01-20 10:10:16
  • ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

Name ZL0454
Description ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
Related Catalog
Target

IC50: 49 nM nM (BD1), 32 nM nM (BD2)[1]

References

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.

Molecular Formula C18H22N4O3S
Molecular Weight 374.46
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