ZL0454

Modify Date: 2024-01-20 10:10:16

ZL0454 Structure
ZL0454 structure
Common Name ZL0454
CAS Number 2229042-77-5 Molecular Weight 374.46
Density N/A Boiling Point N/A
Molecular Formula C18H22N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ZL0454


ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

 Names

Name ZL0454

 ZL0454 Biological Activity

Description ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
Related Catalog
Target

IC50: 49 nM nM (BD1), 32 nM nM (BD2)[1]

References

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.

 Chemical & Physical Properties

Molecular Formula C18H22N4O3S
Molecular Weight 374.46
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