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  • DC Chemicals Limited
  • China
  • Product Name: Jak-in-3
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

1400876-94-9

1400876-94-9 structure
1400876-94-9 structure
  • Name: Jak-in-3
  • Chemical Name: JAK-IN-3
  • CAS Number: 1400876-94-9
  • Molecular Formula: C18H20N4O3
  • Molecular Weight: 340.38
  • Catalog: Signaling Pathways Epigenetics JAK
  • Create Date: 2019-06-01 13:10:27
  • Modify Date: 2024-01-10 14:04:01
  • JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].

Name JAK-IN-3
Description JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].
Related Catalog
Target

JAK3:3 nM (IC50)

JAK1:5 nM (IC50)

Tyk2:34 nM (IC50)

JAK2:70 nM (IC50)

References

[1]. Spergel SH, et al. Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

Molecular Formula C18H20N4O3
Molecular Weight 340.38