1357349-91-7
1357349-91-7 structure
- Name: SPP 86
- Chemical Name: SPP-86
- CAS Number: 1357349-91-7
- Molecular Formula: C16H15N5
- Molecular Weight: 277.32
- Catalog: Research Areas Cancer
- Create Date: 2019-06-01 19:07:34
- Modify Date: 2024-01-04 21:01:25
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SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 selectively inhibits RET- induced ERK1/2 phosphorylation in thyroid cancer cell lines[1].
| Name | SPP-86 |
|---|
| Description | SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. SPP-86 selectively inhibits RET- induced ERK1/2 phosphorylation in thyroid cancer cell lines[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 8 nM (RET)[1]. |
| References |
| Molecular Formula | C16H15N5 |
|---|---|
| Molecular Weight | 277.32 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |