2243076-67-5
2243076-67-5 structure
- Name: ZXH 3-26
- Chemical Name: ZXH-3-26
- CAS Number: 2243076-67-5
- Molecular Formula: C38H37ClN8O7S
- Molecular Weight: 785.27
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2019-06-01 18:07:14
- Modify Date: 2024-01-14 14:07:07
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ZXH-3-26 is a selective BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM[1].
| Name | ZXH-3-26 |
|---|
| Description | ZXH-3-26 is a selective BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
BRD4:5 nM (DC50, 5 hours of treatment) |
| In Vitro | ZXH-3-26 represents the first small molecule to allow pharmacologic targeting of BRD4 without significant inhibition or degradation of BRD2/3[1]. |
| References |
| Molecular Formula | C38H37ClN8O7S |
|---|---|
| Molecular Weight | 785.27 |
| Hazard Codes | Xi |
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