ZXH 3-26

Modify Date: 2024-01-14 14:07:07

ZXH 3-26 structure	Common Name	ZXH 3-26
	CAS Number	2243076-67-5	Molecular Weight	785.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₃₇ClN₈O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZXH 3-26

ZXH-3-26 is a selective BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM[1].

Name	ZXH-3-26

Description	ZXH-3-26 is a selective BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4:5 nM (DC50, 5 hours of treatment)
In Vitro	ZXH-3-26 represents the first small molecule to allow pharmacologic targeting of BRD4 without significant inhibition or degradation of BRD2/3[1].
References	[1]. Nowak RP, et al. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 2018 Jul;14(7):706-714.

Molecular Formula	C₃₈H₃₇ClN₈O₇S
Molecular Weight	785.27

Hazard Codes	Xi

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ZXH 3-26
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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