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  • DC Chemicals Limited
  • China
  • Product Name: MF-438
  • Price: $550.0/100mg $950.0/250mg $1800.0/1g
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Tony Cao

921605-87-0

921605-87-0 structure
921605-87-0 structure

Name MF-438
Description MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].
Related Catalog
Target

EC50: 2.3 nM (rSCD1)[1]

In Vivo MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
References

[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

Molecular Formula C19H18F3N5OS
Molecular Weight 421.44