Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MF-438
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MF-438
Price: $550.0/100mg $950.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: MF-438
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

921605-87-0

921605-87-0 structure

921605-87-0 structure

Name: MF-438
Chemical Name: MF-438
CAS Number: 921605-87-0
Molecular Formula: C₁₉H₁₈F₃N₅OS
Molecular Weight: 421.44
Catalog: Signaling Pathways Metabolic Enzyme/Protease Stearoyl-CoA Desaturase (SCD)
Create Date: 2019-06-29 21:01:05
Modify Date: 2024-04-13 17:09:10
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].

Name	MF-438

Description	MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Stearoyl-CoA Desaturase (SCD) Research Areas >> Metabolic Disease
Target	EC50: 2.3 nM (rSCD1)[1]
In Vivo	MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
References	[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

Molecular Formula	C₁₉H₁₈F₃N₅OS
Molecular Weight	421.44

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