MF-438

Modify Date: 2024-04-13 17:09:10

MF-438 structure	Common Name	MF-438
	CAS Number	921605-87-0	Molecular Weight	421.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₈F₃N₅OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MF-438

MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].

Name	MF-438

Description	MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Stearoyl-CoA Desaturase (SCD) Research Areas >> Metabolic Disease
Target	EC50: 2.3 nM (rSCD1)[1]
In Vivo	MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
References	[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

Molecular Formula	C₁₉H₁₈F₃N₅OS
Molecular Weight	421.44

DC Chemicals Limited
China
Product Name: MF438
Price: $550.0/100mg $950.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Tony Cao

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