2101765-81-3
2101765-81-3 structure
- Name: DRI-C21045
- Chemical Name: DRI-C21045
- CAS Number: 2101765-81-3
- Molecular Formula: C33H26N2O6S
- Molecular Weight: 578.63
- Catalog: Signaling Pathways Apoptosis TNF Receptor
- Create Date: 2019-10-31 12:01:06
- Modify Date: 2024-01-12 19:10:52
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DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively[1].
| Name | DRI-C21045 |
|---|
| Description | DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 0.17 µM (CD40)[1] |
| References |
| Molecular Formula | C33H26N2O6S |
|---|---|
| Molecular Weight | 578.63 |