DRI-C21045
Modify Date: 2024-01-12 19:10:52
DRI-C21045 structure
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Common Name | DRI-C21045 | ||
|---|---|---|---|---|
| CAS Number | 2101765-81-3 | Molecular Weight | 578.63 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C33H26N2O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DRI-C21045DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively[1]. |
| Name | DRI-C21045 |
|---|
| Description | DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 0.17 µM (CD40)[1] |
| References |
| Molecular Formula | C33H26N2O6S |
|---|---|
| Molecular Weight | 578.63 |