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1639220-15-7

1639220-15-7 structure
1639220-15-7 structure
  • Name: Sigma-1 receptor antagonist 2
  • Chemical Name: Sigma-1 receptor antagonist 2
  • CAS Number: 1639220-15-7
  • Molecular Formula: C20H26ClN3O2
  • Molecular Weight: 375.89
  • Create Date: 2019-12-08 19:00:19
  • Modify Date: 2024-01-18 21:21:00
  • Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].

Name Sigma-1 receptor antagonist 2
Description Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].
Target

Ki: 3.88 nM (σ1 receptor), 1288 nM (σ2 receptor)[1]

References

[1]. Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

Molecular Formula C20H26ClN3O2
Molecular Weight 375.89