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1254318-44-9

1254318-44-9 structure
1254318-44-9 structure
  • Name: AZD-5248
  • Chemical Name: 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano-4-biphenylyl)ethyl]tetrahydro-2H-pyran-4-carboxamide
  • CAS Number: 1254318-44-9
  • Molecular Formula: C22H22N4O2
  • Molecular Weight: 374.436
  • Create Date: 2020-01-12 11:08:49
  • Modify Date: 2024-09-04 08:07:50
  • AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).

Name 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano-4-biphenylyl)ethyl]tetrahydro-2H-pyran-4-carboxamide
Synonyms 4-Amino-N-[(1S)-1-cyano-2-(4'-cyano-4-biphenylyl)ethyl]tetrahydro-2H-pyran-4-carboxamide
2H-Pyran-4-carboxamide, 4-amino-N-[(1S)-1-cyano-2-(4'-cyano[1,1'-biphenyl]-4-yl)ethyl]tetrahydro-
Description AZD-5248 is a potent, selective, first generation, oral inhibitor of dipeptidyl peptidase 1 (DPP1).
References References 1. Bragg RA, et al. Chem Res Toxicol. 2015 Oct 19;28(10):1991-9. View Related Products by Target Dipeptidyl Peptidase (DPP)
Density 1.3±0.1 g/cm3
Boiling Point 685.2±55.0 °C at 760 mmHg
Molecular Formula C22H22N4O2
Molecular Weight 374.436
Flash Point 368.2±31.5 °C
Exact Mass 374.174286
LogP 1.40
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.625
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