733807-13-1

733807-13-1 structure

Name: CID 9998128
Chemical Name: N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine
CAS Number: 733807-13-1
Molecular Formula: C₂₁H₁₆N₆
Molecular Weight: 352.392
Create Date: 2020-01-11 15:14:52
Modify Date: 2023-01-14 10:57:19
CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils; strongly binds to both amyloid beta 42 (Aβ42) fibrils and β-secretase and the van der Waals interaction is dominating over the electrostatic interaction in binding affinity.

Name	N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine
Synonyms	4-Quinazolinamine, N-1H-indazol-5-yl-2-(6-methyl-2-pyridinyl)- N-(1H-Indazol-5-yl)-2-(6-methyl-2-pyridinyl)-4-quinazolinamine N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine

Description	CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils; strongly binds to both amyloid beta 42 (Aβ42) fibrils and β-secretase and the van der Waals interaction is dominating over the electrostatic interaction in binding affinity.
References	References 1. Thai NQ, et al. ACS Chem Neurosci. 2018 May 18. doi: 10.1021/acschemneuro.8b00091. View Related Products by Target Amyloids