2109805-80-1
2109805-80-1 structure
- Name: BRD-4592
- Chemical Name: BRD-4592
- CAS Number: 2109805-80-1
- Molecular Formula: C17H15FN2O
- Molecular Weight: 282.318
- Create Date: 2020-01-12 14:07:50
- Modify Date: 2025-09-02 03:56:46
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A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.
| Name | BRD-4592 |
|---|
| Description | A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo. |
|---|---|
| References | References 1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96. View Related Products by Target Bacterial |
| Molecular Formula | C17H15FN2O |
|---|---|
| Molecular Weight | 282.318 |