BRD-4592

Modify Date: 2024-04-05 17:21:14

BRD-4592 Structure
BRD-4592 structure
Common Name BRD-4592
CAS Number 2109805-80-1 Molecular Weight 282.318
Density N/A Boiling Point N/A
Molecular Formula C17H15FN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BRD-4592


A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.

 Names

Name BRD-4592

 BRD-4592 Biological Activity

Description A small-molecule, allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase (TrpAB); binds at the TrpAB α-β-subunit interface with IC50 of 70.9 nM and 22.6 nM for α-subunit and β-subunit, respectively; highly effective in vivo.
References References 1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96. View Related Products by Target Bacterial

 Chemical & Physical Properties

Molecular Formula C17H15FN2O
Molecular Weight 282.318
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