1240494-14-7
1240494-14-7 structure
- Name: SX-576
- Chemical Name: SX-576
- CAS Number: 1240494-14-7
- Molecular Formula: C20H15BF4N2O4S
- Molecular Weight: 466.214
- Create Date: 2020-01-14 14:48:13
- Modify Date: 2023-01-16 07:42:36
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A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.
| Name | SX-576 |
|---|
| Description | A potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively; exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation. |
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| References | References 1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4. 2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. View Related Products by Target Chemokine Receptor (CCR and CXCR) |
| Molecular Formula | C20H15BF4N2O4S |
|---|---|
| Molecular Weight | 466.214 |