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  • DC Chemicals Limited
  • China
  • Product Name: MPK-09
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

1431884-83-1

1431884-83-1 structure
1431884-83-1 structure
  • Name: MPK-09
  • Chemical Name: MPK-09
  • CAS Number: 1431884-83-1
  • Molecular Formula: C24H34O6
  • Molecular Weight: 418.53
  • Create Date: 2020-01-20 09:42:56
  • Modify Date: 2024-01-10 10:21:27
  • A highly potent, selective mutant p53 (R175H, R249S, R273H, R273C) reactivator; exhibits potent cytotoxic activity against BT474 (p53 E285K) cell line (IC50=0.6 uM) as compared to wt p53 A549 (IC50=2.8 uM) and HeLa (IC50 = 4 uM) cells; enhances PARP cleavage, activates caspase 3 expressions and induces apoptosis.

Name MPK-09
Description A highly potent, selective mutant p53 (R175H, R249S, R273H, R273C) reactivator; exhibits potent cytotoxic activity against BT474 (p53 E285K) cell line (IC50=0.6 uM) as compared to wt p53 A549 (IC50=2.8 uM) and HeLa (IC50 = 4 uM) cells; enhances PARP cleavage, activates caspase 3 expressions and induces apoptosis.
References References 1. Metri PK, et al. ACS Chem Biol. 2013 Jul 19;8(7):1429-34. View Related Products by Target MDM2-p53
Molecular Formula C24H34O6
Molecular Weight 418.53