356776-32-4

356776-32-4 structure
356776-32-4 structure
  • Name: AG-09/1
  • Chemical Name: 2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(4-nitrophenyl)acetamide
  • CAS Number: 356776-32-4
  • Molecular Formula: C16H14N4O4S
  • Molecular Weight: 358.37200
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2016-02-09 20:09:55
  • Modify Date: 2024-01-16 13:14:48
  • AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense[1].

Name 2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(4-nitrophenyl)acetamide
Synonyms 2-[(6-methoxy-1H-benzimidazol-2-yl)thio]-N-(4-nitrophenyl)-acetamide
Description AG-09/1 is a specific formyl peptide receptor 1 (FPR1) agonist. N-formyl peptide receptors (FPR) are important in host defense[1].
Related Catalog
Target

FPR1[1]

In Vitro N-formyl peptides activate phagocytes through G protein-coupled receptors known as FPR. FPR1 was the first FPR cloned and encodes a high-affinity receptor for fMLF[1].
References

[1]. Andrei I Khlebnikov, et al. Computational Structure-Activity Relationship Analysis of Small-Molecule Agonists for Human Formyl Peptide Receptors. Eur J Med Chem. 2010 Nov;45(11):5406-19.

Molecular Formula C16H14N4O4S
Molecular Weight 358.37200
Exact Mass 358.07400
PSA 138.13000
LogP 3.80670
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
RIDADR NONH for all modes of transport
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