1448419-13-3
1448419-13-3 structure
- Name: PDE5-IN-6c
- Chemical Name: PDE5-IN-6c
- CAS Number: 1448419-13-3
- Molecular Formula: C23H21ClN4O2
- Molecular Weight: 420.897
- Create Date: 2020-01-12 14:32:50
- Modify Date: 2024-08-19 12:24:30
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A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease.
| Name | PDE5-IN-6c |
|---|
| Description | A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease. |
|---|---|
| References | References 1. Fiorito J, et al. J Med Chem. 2017 Nov 9;60(21):8858-8875. View Related Products by Target Phosphodiesterase (PDE) |
| Molecular Formula | C23H21ClN4O2 |
|---|---|
| Molecular Weight | 420.897 |