PDE5-IN-6c

Modify Date: 2024-08-19 12:24:30

PDE5-IN-6c Structure
PDE5-IN-6c structure
Common Name PDE5-IN-6c
CAS Number 1448419-13-3 Molecular Weight 420.897
Density N/A Boiling Point N/A
Molecular Formula C23H21ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PDE5-IN-6c


A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease.

 Names

Name PDE5-IN-6c

 PDE5-IN-6c Biological Activity

Description A novel potent, selective PDE5 inhibitor with IC50 of 0.056 nM for PDE5A1; displays >500-fold selectivity over PDE6; exhibits good efficacy in mouse model of Alzheimer's disease.
References References 1. Fiorito J, et al. J Med Chem. 2017 Nov 9;60(21):8858-8875. View Related Products by Target Phosphodiesterase (PDE)

 Chemical & Physical Properties

Molecular Formula C23H21ClN4O2
Molecular Weight 420.897
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