1914944-54-9
1914944-54-9 structure
- Name: ROMK-IN-32
- Chemical Name: ROMK-IN-32
- CAS Number: 1914944-54-9
- Molecular Formula: C24H28N4O5
- Molecular Weight: 452.511
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2020-01-13 08:57:23
- Modify Date: 2024-07-22 08:20:46
-
ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM; shows an improved functional hERG/ROMK potency ratio (1176x) and preclinical PK profile; demonstrates blood pressure lowering effects in the spontaneously hypertensive rat model.
| Name | ROMK-IN-32 |
|---|
| Description | ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM; shows an improved functional hERG/ROMK potency ratio (1176x) and preclinical PK profile; demonstrates blood pressure lowering effects in the spontaneously hypertensive rat model. |
|---|---|
| References | References 1. Dong S, et al. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2559-2566. View Related Products by Target Potassium Channel |
| Molecular Formula | C24H28N4O5 |
|---|---|
| Molecular Weight | 452.511 |
| Hazard Codes | Xi |
|---|