ROMK-IN-32

Modify Date: 2024-07-22 08:20:46

ROMK-IN-32 Structure
ROMK-IN-32 structure
Common Name ROMK-IN-32
CAS Number 1914944-54-9 Molecular Weight 452.511
Density N/A Boiling Point N/A
Molecular Formula C24H28N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ROMK-IN-32


ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM; shows an improved functional hERG/ROMK potency ratio (1176x) and preclinical PK profile; demonstrates blood pressure lowering effects in the spontaneously hypertensive rat model.

 Names

Name ROMK-IN-32

 ROMK-IN-32 Biological Activity

Description ROMK-IN-32 is a potent, selective ROMK inhibitor with IC50 of 17 nM; shows an improved functional hERG/ROMK potency ratio (1176x) and preclinical PK profile; demonstrates blood pressure lowering effects in the spontaneously hypertensive rat model.
References References 1. Dong S, et al. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2559-2566. View Related Products by Target Potassium Channel

 Chemical & Physical Properties

Molecular Formula C24H28N4O5
Molecular Weight 452.511

 Safety Information

Hazard Codes Xi
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