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2162951-06-4

2162951-06-4 structure
2162951-06-4 structure
  • Name: SHP2-IN-2
  • Chemical Name: SHP2-IN-2
  • CAS Number: 2162951-06-4
  • Molecular Formula: C17H11ClN2O2S
  • Molecular Weight: 342.797
  • Create Date: 2020-01-11 21:22:45
  • Modify Date: 2024-04-05 15:14:06
  • SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.

Name SHP2-IN-2
Description SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.
References References 1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485. View Related Products by Target Protein Phosphatase/PTP
Molecular Formula C17H11ClN2O2S
Molecular Weight 342.797
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