2162951-06-4
2162951-06-4 structure
- Name: SHP2-IN-2
- Chemical Name: SHP2-IN-2
- CAS Number: 2162951-06-4
- Molecular Formula: C17H11ClN2O2S
- Molecular Weight: 342.797
- Create Date: 2020-01-11 21:22:45
- Modify Date: 2025-09-12 15:25:22
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SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.
| Name | SHP2-IN-2 |
|---|
| Description | SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM. |
|---|---|
| References | References 1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485. View Related Products by Target Protein Phosphatase/PTP |
| Molecular Formula | C17H11ClN2O2S |
|---|---|
| Molecular Weight | 342.797 |