SHP2-IN-2 structure
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Common Name | SHP2-IN-2 | ||
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CAS Number | 2162951-06-4 | Molecular Weight | 342.797 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H11ClN2O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of SHP2-IN-2SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM. |
Name | SHP2-IN-2 |
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Description | SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM. |
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References | References 1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485. View Related Products by Target Protein Phosphatase/PTP |
Molecular Formula | C17H11ClN2O2S |
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Molecular Weight | 342.797 |