SHP2-IN-2

Modify Date: 2024-04-05 15:14:06

SHP2-IN-2 Structure
SHP2-IN-2 structure
Common Name SHP2-IN-2
CAS Number 2162951-06-4 Molecular Weight 342.797
Density N/A Boiling Point N/A
Molecular Formula C17H11ClN2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SHP2-IN-2


SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.

 Names

Name SHP2-IN-2

 SHP2-IN-2 Biological Activity

Description SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.
References References 1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485. View Related Products by Target Protein Phosphatase/PTP

 Chemical & Physical Properties

Molecular Formula C17H11ClN2O2S
Molecular Weight 342.797
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