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  • DC Chemicals Limited
  • China
  • Product Name: SB-357134
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

219963-52-7

219963-52-7 structure
219963-52-7 structure
  • Name: SB-357134
  • Chemical Name: SB-357134
  • CAS Number: 219963-52-7
  • Molecular Formula: C17H18Br2FN3O3S
  • Molecular Weight: 523.22
  • Create Date: 2020-01-11 21:05:46
  • Modify Date: 2024-04-04 02:00:48
  • A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5, displays 1300-fold selectivity over other 13 5-HT receptor subtypes; inhibits 5-HT-stimulated cAMP accumulation in with pA2 of 7.63, enhances memory and learning following chronic administration in mice.

Name SB-357134
Description A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5, displays 1300-fold selectivity over other 13 5-HT receptor subtypes; inhibits 5-HT-stimulated cAMP accumulation in with pA2 of 7.63, enhances memory and learning following chronic administration in mice.
References References 1. Bromidge SM, et al. Bioorg Med Chem Lett. 2001 Jan 8;11(1):55-8. 2. Stean TO, et al. Pharmacol Biochem Behav. 2002 Apr;71(4):645-54. 3. Marcos B, et al. Eur J Neurosci. 2006 Sep;24(5):1299-306. 4. Rogers DC, et al. Psychopharmacology (Berl). 2001 Nov;158(2):114-9. View Related Products by Target 5-HT Receptor
Molecular Formula C17H18Br2FN3O3S
Molecular Weight 523.22