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947540-06-9

947540-06-9 structure
947540-06-9 structure
  • Name: MAO-B inhibitor 8f
  • Chemical Name: MAO-B inhibitor 8f
  • CAS Number: 947540-06-9
  • Molecular Formula: C15H16F3N3O2S
  • Molecular Weight: 359.367
  • Create Date: 2020-01-11 18:21:51
  • Modify Date: 2024-02-04 23:35:31
  • A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.

Name MAO-B inhibitor 8f
Description A novel potent, selective monoamine oxidase B (MAO-B) inhibitor with IC50 of 29-56 nM; shows no significant activity over MAO-A (>10 uM); shows improvement for memory in multiple animal models, has an excellent profile against a panel of other enzymes and receptors, good pharmacokinetic properties in rodents and dogs.
References References 1. Kaplan A, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2746-2758. View Related Products by Target Monoamine Oxidase (MAO)
Molecular Formula C15H16F3N3O2S
Molecular Weight 359.367