1832646-52-2
1832646-52-2 structure
- Name: GLS1 Inhibitor
- Chemical Name: GLS1 Inhibitor
- CAS Number: 1832646-52-2
- Molecular Formula: C19H21N7O2S
- Molecular Weight: 411.5
- Create Date: 2020-01-20 16:29:57
- Modify Date: 2024-01-10 19:39:05
-
GLS1 inhibitor is an inhibitor of glutaminase 1
| Name | GLS1 Inhibitor |
|---|
| Description | GLS1 inhibitor is an inhibitor of glutaminase 1 |
|---|---|
| In Vitro | GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50 = 0.021 μM).1 It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. |
| Molecular Formula | C19H21N7O2S |
|---|---|
| Molecular Weight | 411.5 |