GLS1 Inhibitor
Modify Date: 2024-01-10 19:39:05
GLS1 Inhibitor structure
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Common Name | GLS1 Inhibitor | ||
|---|---|---|---|---|
| CAS Number | 1832646-52-2 | Molecular Weight | 411.5 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H21N7O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GLS1 InhibitorGLS1 inhibitor is an inhibitor of glutaminase 1 |
| Name | GLS1 Inhibitor |
|---|
| Description | GLS1 inhibitor is an inhibitor of glutaminase 1 |
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| In Vitro | GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50 = 0.021 μM).1 It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. |
| Molecular Formula | C19H21N7O2S |
|---|---|
| Molecular Weight | 411.5 |