863239-61-6
863239-61-6 structure
- Name: Tauro-Obeticholic acid
- Chemical Name: Tauro-Obeticholic acid
- CAS Number: 863239-61-6
- Molecular Formula: C28H49NO6S
- Molecular Weight: 527.76
- Catalog: Signaling Pathways Metabolic Enzyme/Protease FXR
- Create Date: 2020-01-23 11:50:51
- Modify Date: 2025-08-26 17:07:08
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Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].
| Name | Tauro-Obeticholic acid |
|---|
| Description | Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1]. |
| References |
[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |
| Molecular Formula | C28H49NO6S |
|---|---|
| Molecular Weight | 527.76 |