Tauro-Obeticholic acid

Modify Date: 2024-01-10 10:07:13

Tauro-Obeticholic acid Structure
Tauro-Obeticholic acid structure
Common Name Tauro-Obeticholic acid
CAS Number 863239-61-6 Molecular Weight 527.76
Density N/A Boiling Point N/A
Molecular Formula C28H49NO6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tauro-Obeticholic acid


Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].

 Names

Name Tauro-Obeticholic acid

 Tauro-Obeticholic acid Biological Activity

Description Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].
Related Catalog
In Vitro Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].
References

[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6.

 Chemical & Physical Properties

Molecular Formula C28H49NO6S
Molecular Weight 527.76
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