Tauro-Obeticholic acid structure
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Common Name | Tauro-Obeticholic acid | ||
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CAS Number | 863239-61-6 | Molecular Weight | 527.76 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C28H49NO6S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Tauro-Obeticholic acidTauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1]. |
Name | Tauro-Obeticholic acid |
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Description | Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1]. |
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Related Catalog | |
In Vitro | Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1]. |
References |
[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |
Molecular Formula | C28H49NO6S |
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Molecular Weight | 527.76 |