30426-66-5

30426-66-5 structure

Name: Pseudocoptisine acetate
Chemical Name: Pseudocoptisine acetate
CAS Number: 30426-66-5
Molecular Formula: C₂₁H₁₇NO₆
Molecular Weight: 379.36
Catalog: Signaling Pathways MAPK/ERK Pathway ERK
Create Date: 2020-04-23 16:09:26
Modify Date: 2024-01-12 09:10:52
Pseudocoptisine acetate, a quaternary alkaloid with a benzylisoquinoline skeleton, is isolated from the tubers of Corydalis turtschaninovii. Pseudocoptisine acetate shows anti-inflammatory properties[1].

Name	Pseudocoptisine acetate

Description	Pseudocoptisine acetate, a quaternary alkaloid with a benzylisoquinoline skeleton, is isolated from the tubers of Corydalis turtschaninovii. Pseudocoptisine acetate shows anti-inflammatory properties[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
In Vitro	Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells[1].
References	[1]. Yun KJ, et al. Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage cells. Int Immunopharmacol. 2009 Oct;9(11):1323-31.

Molecular Formula	C₂₁H₁₇NO₆
Molecular Weight	379.36