2062663-68-5

2062663-68-5 structure

2062663-68-5 structure

Name: Boc-aminoxy-PEG4-acid
Chemical Name: Boc-aminoxy-PEG4-acid
CAS Number: 2062663-68-5
Molecular Formula: C₁₆H₃₁NO₉
Molecular Weight: 381.42
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 05:13:27
Modify Date: 2024-01-09 11:19:40
Boc-aminoxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-aminoxy-PEG4-acid

Description	Boc-aminoxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₃₁NO₉
Molecular Weight	381.42