2353409-84-2

2353409-84-2 structure

2353409-84-2 structure

Name: Diketone-PEG4-PFP ester
Chemical Name: Diketone-PEG4-PFP ester
CAS Number: 2353409-84-2
Molecular Formula: C₃₀H₃₄F₅NO₉
Molecular Weight: 647.58
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:31:02
Modify Date: 2024-01-11 18:25:08
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Diketone-PEG4-PFP ester

Description	Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₀H₃₄F₅NO₉
Molecular Weight	647.58