2353409-58-0

2353409-58-0 structure
2353409-58-0 structure
  • Name: N-(Azido-PEG3)-N-bis(PEG4-Boc)
  • Chemical Name: N-(Azido-PEG3)-N-bis(PEG4-Boc)
  • CAS Number: 2353409-58-0
  • Molecular Formula: C38H74N4O15
  • Molecular Weight: 827.01
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:02:54
  • Modify Date: 2024-04-06 08:58:44
  • N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG3)-N-bis(PEG4-Boc)
Description N-(Azido-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C38H74N4O15
Molecular Weight 827.01
Hazard Codes Xi