2112731-48-1

2112731-48-1 structure

2112731-48-1 structure

Name: N-(Biotin-PEG4)-N-bis(PEG4-acid)
Chemical Name: N-(Biotin-PEG4)-N-bis(PEG4-acid)
CAS Number: 2112731-48-1
Molecular Formula: C₄₂H₇₈N₄O₁₈S
Molecular Weight: 959.15
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 10:13:06
Modify Date: 2024-01-09 07:46:31
N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Biotin-PEG4)-N-bis(PEG4-acid)
Synonyms	MFCD30723243

Description	N-(Biotin-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₂H₇₈N₄O₁₈S
Molecular Weight	959.15