151804-79-4

151804-79-4 structure

Name: AC 253
Chemical Name: AC 253
CAS Number: 151804-79-4
Molecular Formula: C₁₂₂H₁₉₆N₄₀O₃₉
Molecular Weight: 2847.11
Create Date: 2020-08-10 19:23:54
Modify Date: 2025-08-29 07:17:28
AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.

Name	AC 253

Description	AC 253 is an Amylin (AMY3) receptor antagonist, inhibiting andrenomedulin-stimulated cAMP production. AC 253 protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. AC 253 blocks electrophysiological effects of Aβ.