2341796-77-6
2341796-77-6 structure
- Name: (S,R,S)-AHPC-C6-NH2 dihydrochloride
- Chemical Name: (S,R,S)-AHPC-C6-NH2 dihydrochloride
- CAS Number: 2341796-77-6
- Molecular Formula: C29H45Cl2N5O4S
- Molecular Weight: 630.67
- Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
- Create Date: 2020-08-10 20:51:00
- Modify Date: 2024-04-08 19:17:56
-
(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
| Name | (S,R,S)-AHPC-C6-NH2 dihydrochloride |
|---|
| Description | (S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1]. |
|---|---|
| Related Catalog | |
| Target |
VHL |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C29H45Cl2N5O4S |
|---|---|
| Molecular Weight | 630.67 |
| Hazard Codes | Xi |
|---|