2341796-77-6

2341796-77-6 structure

Name: (S,R,S)-AHPC-C6-NH2 dihydrochloride
Chemical Name: (S,R,S)-AHPC-C6-NH2 dihydrochloride
CAS Number: 2341796-77-6
Molecular Formula: C₂₉H₄₅Cl₂N₅O₄S
Molecular Weight: 630.67
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-08-10 20:51:00
Modify Date: 2024-04-08 19:17:56
(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].

Name	(S,R,S)-AHPC-C6-NH2 dihydrochloride

Description	(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

Molecular Formula	C₂₉H₄₅Cl₂N₅O₄S
Molecular Weight	630.67

Hazard Codes	Xi