(S,R,S)-AHPC-C6-NH2 dihydrochloride

Modify Date: 2024-04-08 19:17:56

(S,R,S)-AHPC-C6-NH2 dihydrochloride Structure
(S,R,S)-AHPC-C6-NH2 dihydrochloride structure
Common Name (S,R,S)-AHPC-C6-NH2 dihydrochloride
CAS Number 2341796-77-6 Molecular Weight 630.67
Density N/A Boiling Point N/A
Molecular Formula C29H45Cl2N5O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-C6-NH2 dihydrochloride


(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].

 Names

Name (S,R,S)-AHPC-C6-NH2 dihydrochloride

 (S,R,S)-AHPC-C6-NH2 dihydrochloride Biological Activity

Description (S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
Related Catalog
Target

VHL

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.

 Chemical & Physical Properties

Molecular Formula C29H45Cl2N5O4S
Molecular Weight 630.67

 Safety Information

Hazard Codes Xi
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