2225148-51-4
2225148-51-4 structure
- Name: Thalidomide-O-C8-COOH
- Chemical Name: Thalidomide-O-C8-COOH
- CAS Number: 2225148-51-4
- Molecular Formula: C22H26N2O7
- Molecular Weight: 430.45
- Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
- Create Date: 2020-08-07 14:55:59
- Modify Date: 2025-08-26 01:41:26
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Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].
| Name | Thalidomide-O-C8-COOH |
|---|
| Description | Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| References |
[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1. |
| Molecular Formula | C22H26N2O7 |
|---|---|
| Molecular Weight | 430.45 |
| Hazard Codes | Xi |
|---|