Thalidomide-O-C8-COOH

Modify Date: 2024-01-10 12:50:17

Thalidomide-O-C8-COOH Structure
Thalidomide-O-C8-COOH structure
Common Name Thalidomide-O-C8-COOH
CAS Number 2225148-51-4 Molecular Weight 430.45
Density N/A Boiling Point N/A
Molecular Formula C22H26N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-C8-COOH


Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].

 Names

Name Thalidomide-O-C8-COOH

 Thalidomide-O-C8-COOH Biological Activity

Description Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].
Related Catalog
Target

Cereblon

References

[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.

 Chemical & Physical Properties

Molecular Formula C22H26N2O7
Molecular Weight 430.45

 Safety Information

Hazard Codes Xi
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