2412791-72-9
2412791-72-9 structure
- Name: UNC2399
- Chemical Name: UNC2399
- CAS Number: 2412791-72-9
- Molecular Formula: C48H66N10O7S
- Molecular Weight: 927.17
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2020-11-28 16:37:04
- Modify Date: 2024-01-11 01:19:04
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UNC2399, a biotinylated UNC1999, is a selective EZH2 degrader, maintaining high in vitro potency for EZH2, with an IC50 of 17 nM[1][2].
| Name | UNC2399 |
|---|
| Description | UNC2399, a biotinylated UNC1999, is a selective EZH2 degrader, maintaining high in vitro potency for EZH2, with an IC50 of 17 nM[1][2]. |
|---|---|
| Related Catalog | |
| Target |
EZH2:17 nM (IC50) |
| In Vitro | UNC2399 (1-1000 nM) displays high in vitro potency (IC50=17±2 nM) in the EZH2 radioactive biochemical assay[1]. UNC2399 (100 μM) enriches EZH2 from HEK293T cell lysates[1]. |
| References |
| Molecular Formula | C48H66N10O7S |
|---|---|
| Molecular Weight | 927.17 |