2172819-74-6
2172819-74-6 structure
- Name: VH032-linker 5
- Chemical Name: N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
- CAS Number: 2172819-74-6
- Molecular Formula: C28H38N4O6S
- Molecular Weight: 558.690
- Create Date: 2021-01-09 10:50:10
- Modify Date: 2024-04-08 22:24:12
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VH032-linker 5 is a derivative of the proteolysis-targeting chimera technology (PROTAC) for PROTAC research and development; by incorporating an E3 ligase ligand and an alkyl C4 linker with terminal carboxylic acid, it is ready for conjugation to a target protein ligand.
| Name | N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
|---|---|
| Synonyms |
L-Prolinamide, N-(5-carboxy-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 878.5±65.0 °C at 760 mmHg |
| Molecular Formula | C28H38N4O6S |
| Molecular Weight | 558.690 |
| Flash Point | 485.1±34.3 °C |
| Exact Mass | 558.251221 |
| LogP | 1.17 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.586 |