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2172819-74-6

2172819-74-6 structure
2172819-74-6 structure
  • Name: VH032-linker 5
  • Chemical Name: N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
  • CAS Number: 2172819-74-6
  • Molecular Formula: C28H38N4O6S
  • Molecular Weight: 558.690
  • Create Date: 2021-01-09 10:50:10
  • Modify Date: 2024-04-08 22:24:12
  • VH032-linker 5 is a derivative of the proteolysis-targeting chimera technology (PROTAC) for PROTAC research and development; by incorporating an E3 ligase ligand and an alkyl C4 linker with terminal carboxylic acid, it is ready for conjugation to a target protein ligand.

Name N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
Synonyms L-Prolinamide, N-(5-carboxy-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
Density 1.3±0.1 g/cm3
Boiling Point 878.5±65.0 °C at 760 mmHg
Molecular Formula C28H38N4O6S
Molecular Weight 558.690
Flash Point 485.1±34.3 °C
Exact Mass 558.251221
LogP 1.17
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.586