189209-27-6
- Name: PROTAC Linker 17
- Chemical Name: tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
- CAS Number: 189209-27-6
- Molecular Formula: C17H36N2O7
- Molecular Weight: 380.47700
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-04-29 08:08:23
- Modify Date: 2026-07-16 17:56:19
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PROTAC Linker 17 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 17 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Name | tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate |
|---|---|
| Synonyms |
Boc-amino-PEG-aMine (n=5)
tert-butyl N-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy] ethoxy]ethoxy]ethyl]cbamate O-(2-AMinoethyl)-O'-[2-(Boc-amino)ethyl]tetraethylene Glycol 19-Amino-5,8,11,14,17-pentaoxa-2-azanonadecanoic Acid 1,1-DiMethylethyl Ester Boc-NH-PEG(4)-NH2(19atoMs) NH2-PEG5-NHBOC t-Boc-Amido-PEG6-Amine tert-Butyl (17-amino-3,6,9,12,15-pentaoxahtadecyl)cbamate Boc-NH-PEG(4)-NH2 t-boc-N-amido-PEG5-Amine Boc-N-amido-PEG5-Azide BOC-NH-PEG5-NH2 BocNH-PEG5-CH2CH2NH2/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-amino-, 1,1-dimethylethyl ester NHBoc-PEG5-amine NH2-PEG5-C2-NH-Boc BOC-AMINO-PEG5-AMINE BOC-N-AMIDO-PEG5-NH2 t-boc-N-amido-PEG6-Amine O-(2-Aminoethyl)-O’-[2-(Boc-amino)ethyl]tetraethylene Glycol N1-Boc-3,6,9,12,15-pentaoxahtadecane-1,17-diamine t-boc-N-amido-PEG5-Azide Boc-N-amido-PEG5-Amine 19-Amino-5,8,11,14,17-pentaoxa-2-azanonadecanoic Acid 1,1-Dimethylethyl Ester 5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-amino-, 1,1-dimethylethyl ester Boc-NH-PEG5-CH2CH2NH2 BocNH-PEG5-CH2CH2NH2 O-(2-Aminoethyl)-O′-[2-(Boc-amino)ethyl]tetraethylene Glycol t-BocNH-PEG5-CH2CH2NH2 |
| Description | PROTAC Linker 17 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 17 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| References |
| Molecular Formula | C17H36N2O7 |
|---|---|
| Molecular Weight | 380.47700 |
| Exact Mass | 380.25200 |
| PSA | 113.99000 |
| LogP | 1.45750 |
| Hazard Codes | Xi |
|---|
|
~99%
189209-27-6 |
| Literature: Gerard, Estelle; Meulle, Aline; Feron, Olivier; Marchand-Brynaert, Jacqueline Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
|
~%
189209-27-6 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 586 - 590 |
