1229652-22-5

1229652-22-5 structure

Name: HA-155
Chemical Name: HA-155
CAS Number: 1229652-22-5
Molecular Formula: C₂₄H₁₉BFNO₅S
Molecular Weight: 463.29
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2021-05-03 19:24:13
Modify Date: 2024-01-08 10:30:08
(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].

Name	HA-155
Synonyms	{4-[(4-{(Z)-[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}phenoxy)methyl]phenyl}boronic acid MFCD28016544 HA-155 Boronic acid, B-[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]- HA-130

Description	(E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	Autotaxin[1]
References	[1]. Joncour A, et al. Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors [published correction appears in J Med Chem. 2018 May 10;61(9):4270]. J Med Chem. 2017;60(17):7371-7392.